Pre-implantation Genetic Screening (PGS)

Key Insights at a Glance

• The procedure helps identify genetic defects in embryos before transfer to the uterus.
• Average cost of PGS abroad can be significantly lower than in the U.S.
• Risks are minimal but may include potential damage to embryos during screening.
• Internationally accredited clinics offer high-quality and reliable PGS services.
• Patients usually do not require recovery time as the procedure is non-invasive to the patient.

What is Pre-implantation Genetic Screening (PGS)?

Pre-implantation Genetic Screening (PGS) is a powerful technology used in the field of reproductive medicine to examine embryos for chromosomal abnormalities before they are transferred to the uterus. This genetic testing is typically performed during in vitro fertilization (IVF) cycles to increase the likelihood of a successful pregnancy and to help prevent genetic disorders. PGS involves the removal of a small cell sample from an embryo and analyzing its chromosomal makeup.

Symptoms of Conditions Detected by PGS

• Down syndrome: Trisomy 21, characterized by an extra chromosome 21.
• Cystic fibrosis: A genetic disorder affecting the respiratory and digestive systems.
• Sickle cell disease: A genetic blood disorder causing red blood cells to become misshapen.
• Tay-Sachs disease: A rare disorder that destroys nerve cells in the brain and spinal cord.

Latest Types of PGS available in the World

Type	Description	Advantages
Next-Generation Sequencing (NGS)	Highly detailed analysis of embryo genomes.	Increased accuracy in detecting abnormalities.
Array Comparative Genomic Hybridization (aCGH)	Assesses chromosome numbers and arrangements.	Effective for screening multiple embryos simultaneously.

Safety Concerns Related to PGS Overseas

• Potential damage to embryos during biopsy.
• Accuracy of genetic testing and interpretation of results.
• Regulatory standards vary by country, impacting overall safety and quality.

Risks Associated with PGS Globally

• False positive or negative results leading to the discarding of potentially healthy embryos.
• Emotional and psychological impact of high-stakes decision-making.
• Legal and ethical considerations, especially in jurisdictions with strict genetic screening laws.

Procedure of PGS

PGS typically involves the following steps:

• IVF is performed to retrieve eggs which are then fertilized in a lab.
• Embryos grow until they reach the blastocyst stage.
• A small number of cells are biopsied from each embryo.
• Cells are analyzed for genetic abnormalities.
• Healthy embryos are selected for implantation into the uterus.

Cost of PGS in the World | Compare Prices

Country	Cost
Mexico	$2,500 - $4,000
Turkey	$1,800 - $3,500
Thailand	$2,000 - $3,800
Colombia	$2,200 - $3,600
India	$1,500 - $2,500
Austria	$4,000 - $5,500
USA	$3,500 - $6,000
UK	$3,000 - $4,500

Find Prices for PGS Near You

FAQs Related to PGS Abroad

What does PGS Cost without insurance?

The cost of PGS without insurance typically ranges from $1,500 to $6,000 depending on the country and clinic.

Is PGS legal in all countries?

PGS legality varies by country. Some countries have stringent regulations or even bans on genetic testing of embryos, while others support it under specific conditions.

How accurate is PGS?

PGS is highly accurate, with sensitivity and specificity rates exceeding 98% in detecting chromosomal abnormalities.

Can PGS reduce the risk of miscarriage?

Yes, PGS can significantly reduce the risk of miscarriage by ensuring that only genetically healthy embryos are implanted.

What are the alternatives to PGS?

Alternatives to PGS include Pre-implantation Genetic Diagnosis (PGD) for single gene disorders and non-invasive prenatal testing (NIPT) after embryo implantation.

Book Your PGS Appointment Abroad Today

Explore high-quality and affordable PGS options abroad. Ensure a healthier pregnancy and baby by choosing internationally accredited clinics known for their advanced genetic testing technologies. Take the first step towards a successful pregnancy journey by booking your appointment today!

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