中国北京多发性骨髓瘤CAR-T细胞疗法——Bjorn Simensen在Bioocus Biotech的故事
中国北京的CAR-T免疫疗法：一位挪威患者的故事
Bjorn Simensen 的 Car T 细胞疗法成功案例
在一段非凡的恢复和医学突破之旅中，来自挪威的患者 Bjorn Simensen 在中国北京百奥卡斯生物科技公司接受 CAR T 细胞治疗后，病情获得了两年的持续缓解。
初步诊断和治疗挑战
Bjorn的病程始于2017年9月，当时他出现咳嗽和胸痛症状，最终被诊断为多发性骨髓瘤（IgG lambda）ISS-II。尽管最初接受了化疗和维持治疗，但2021年夏天病情复发，不得不改变治疗方法。
67 岁的 Bjorn Simensen 于 2017 年被诊断出患有多发性骨髓瘤，接受了多次治疗后于 2021 年复发。2022 年 2 月，他在 Bioocus Biotech 接受了 CART 细胞疗法，成功减少了异常浆细胞并解决了睾丸肿胀问题，并于随后出院并进行了定期复诊。 |
在中国北京百奥克斯生物科技寻求先进治疗
2022年2月，Bjorn前往北京 百奥生物科技公司旗下的陆道培医院就诊，详细检查显示病情复发，M蛋白水平升高。卡非佐米和达雷妥尤单抗等传统化疗方案无效，促使他探索CAR-T细胞疗法等替代疗法。
CAR-T细胞的制备和输注
Bjorn接受了氟达拉滨和环磷酰胺的预处理，为CAR-T细胞疗法做准备。在指定的日期，CAR-T细胞被输注，剂量根据他的具体情况而定。尽管输注后出现了中性粒细胞减少和发热，但及时的医疗干预有效地控制了副作用。
积极响应和恢复
接受CAR-T细胞治疗后，Bjorn的右侧睾丸肿胀逐渐消退，表明治疗反应良好。后续骨髓检查显示异常浆细胞显著减少，最终导致第28天骨髓浆细胞检查结果呈阴性。
持续监测和后续护理
在陆道培医院成功接受治疗后，Bjorn 在其所在城市的血液学中心接受定期随访护理，以确保持续监测和支持以维持其缓解状态。
庆祝成就并展望未来
Bjorn 的历程彰显了 CAR-T 细胞疗法在实现多发性骨髓瘤持续缓解和克服相关挑战方面的变革性影响。他的故事为全世界的患者带来了希望，彰显了 Bioocus Biotech 及类似机构在医学科学和个性化治疗方面的进步。
拥抱超越疾病的生命
比约恩的两年持续缓解经历，凸显了探索创新疗法以及在逆境中永不放弃希望的重要性。他的经历激励着其他人寻求先进的医疗解决方案，拥抱超越疾病的生活，在康复的道路上培养乐观和韧性。
中国CAR-T细胞疗法成功案例 Bjorn Story
Keywords: CAR-T细胞疗法成功案例，CAR-T细胞疗法在中国，CAR-T细胞疗法在中国北京，Bioocus Biotech
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