Cleft Lip and Palate: Insights from Misou Plastic

Understanding the Genetic Incidence of Cleft Lip and Palate – Q&A with the Director at Misou Plastic Surgery

Unraveling Cleft Lip & Palate: Genetics & Anti-Aging in SK

Category: Cosmetic Surgery Abroad
Country: South Korea
Procedure: Anti Aging

Cleft lip and palate are congenital conditions that affect many individuals worldwide. In Episode 7 of the Q&A series at Misou Plastic Surgery, the director sheds light on the genetic factors contributing to these conditions. Here’s a detailed guide to the discussion:


What Are Cleft Lip and Palate?

Cleft lip and palate occur when a baby’s lip or mouth does not form properly during pregnancy. This condition can involve:

  • A split in the lip (cleft lip).
  • An opening in the roof of the mouth (cleft palate).
  • A combination of both.

The Genetic Connection

  • Inheritance Patterns: Cleft lip and palate can run in families, with a multifactorial inheritance pattern involving both genetic and environmental factors.
  • Risk Factors:
    • A parent with a cleft lip or palate may increase the likelihood of passing it on to their children.
    • Mutations in specific genes, such as IRF6, PAX9, or MSX1, are commonly associated.
  • Ethnic and Regional Variations: Genetic predisposition may vary across populations, with some ethnic groups having higher incidence rates.

Environmental Influences

While genetics play a significant role, environmental factors such as maternal smoking, certain medications, and nutritional deficiencies during pregnancy can also contribute to the risk.


Q&A Highlights with the Director

  1. What percentage of cleft lip and palate cases are genetic?
    • The director explains that approximately 20–30% of cases have a direct genetic link.
  2. Are there tests to determine genetic risk?
    • Yes, genetic counseling and testing can help assess risks for prospective parents.
  3. What can families do to reduce risks?
    • Prioritize prenatal care, avoid harmful substances, and consult a specialist if there’s a family history.

Why Understanding Genetics Matters

Recognizing the genetic factors behind cleft lip and palate can help families plan effectively, seek early intervention, and pursue treatments like those available at Misou Plastic Surgery.


For personalized insights and professional care, consult the specialists at MISOU Plastic Surgery, where comprehensive solutions for cleft lip and palate are tailored to individual needs.

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Cleft Lip and Palate: Insights from Misou Plastic

Keywords: Cleft Lip and Palate: Insights from Misou Plastic

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